The introduction of carbon dioxide into the abdominal cavity during laparoscopic abdominal surgery can cause a number of problems with the kidneys. Because obesity is associated with various metabolic conditions and with kidney-related effects, Argalious et al hypothesized that an increased body mass index (BMI) is associated with an increased incidence of postoperative acute kidney injury in patients who have intraabdominal laparoscopic surgery.
The researchers analyzed data for 8,543 patients, 62% of whom were obese according to the World Health Organization BMI classification. They did not prove their hypothesis.
The results showed that obesity per se is not associated with an increased risk of AKI after noncardiac laparoscopic surgery; however, comorbidities that are frequently associated with obesity—diabetes mellitus, hypertension, coronary artery disease, and chronic obstructive pulmonary disease—might increase the odds of developing a more serious level of AKI by 7% for each 5-unit increase in BMI.